| Date | Location | Result | |
| 03/02/10 | Allendale, Mich. (GVSU Fieldhouse Arena) | Grand Valley 47, Wayne State 44 | Box score |
| 02/27/10 | Big Rapids, Mich. | Wayne State 85, Ferris State 78 | Box score |
| 02/25/10 | Allendale, Mich. (GVSU Fieldhouse Arena) | Wayne State 70, Grand Valley 56 | Box score |
| 02/20/10 | Detroit, Michigan (Matthaei) | Wayne State 91, Tiffin University 74 | Box score |
| 02/18/10 | Detroit, Michigan (Matthaei) | Wayne State 74, Ashland University 63 | Box score |
| 02/13/10 | Detroit, Michigan (Matthaei) | Findlay 101, Wayne State 99 | Box score |
| 02/11/10 | Detroit, Michigan (Matthaei) | Hillsdale College 68, Wayne State 65 | Box score |
| 02/06/10 | Sault Ste. Marie, Mich. (Cooper Gym) | Lake Superior 55, Wayne State 53 | Box score |
| 02/04/10 | University Center, Mich. | Saginaw Valley 68, Wayne State 63 | Box score |
| 01/30/10 | Kates Gymnasium; Ashland, Ohio | Wayne State 79, Ashland University 62 | Box score |
| 01/28/10 | Tiffin, Ohio | Wayne State 73, Tiffin University 58 | Box score |
| 01/23/10 | Detroit, Michigan (Matthaei) | Grand Valley 57, Wayne State 48 | Box score |
| 01/21/10 | Detroit, Michigan (Matthaei) | Ferris State 54, Wayne State 52 | Box score |
| 01/16/10 | Detroit, Michigan (Matthaei) | Wayne State 73, Lake Superior 61 | Box score |
| 01/14/10 | Detroit, Michigan (Matthaei) | Saginaw Valley 56, Wayne State 53 | Box score |
| 01/09/10 | Hillsdale, Mich. | Hillsdale College 71, Wayne State 60 | Box score |
| 01/07/10 | Findlay, Ohio | Findlay 88, Wayne State 65 | Box score |
| 01/02/10 | Detroit, Michigan (Matthaei) | Wayne State 64, Northwood 53 | Box score |
| 12/19/09 | Detroit, Michigan (Matthaei) | Wayne State 67, Michigan Tech 58 | Box score |
| 12/17/09 | Detroit, Michigan (Matthaei) | Wayne State 65, Northern Michigan 48 | Box score |
| 12/12/09 | Romeoville, IL (Neil Carey Arena) | Lewis 61, Wayne State 49 | Box score |
| 12/09/09 | Bennett Center - Midland, Mich. | Northwood 94, Wayne State 85 | Box score |
| 12/05/09 | Marquette, Mich. | Wayne State 67, Northern Michigan 60 | Box score |
| 12/03/09 | SDC Gym, Houghton, Mich. | Wayne State 61, Michigan Tech 58 | Box score |
| 11/24/09 | Detroit, Michigan (Matthaei) | Wayne State 79, Marygrove 59 | Box score |
| 11/21/09 | Detroit, Michigan (Matthaei) | Wayne State 84, Bellarmine 74 | Box score |
| 11/17/09 | Wilberforce, Ohio | Central State University 72, Wayne State 68 | Box score |